Port-A-Cath in children during long-term chemotherapy: complications and outcome

Complications related to Port-A-Cath were studied prospectively during a period of 32 months in 31 patients, aged 1-18 years, with leukemias and solid tumors. There were 34 Port-A-Cath inserted, and the cumulative time for these catheters kept in place was 5899 days. No complications occurred in 18 patients (19 catheters) kept in place for a cumulative time of 3998 days with an average duration of 210 days (12-550 days). In 13 patients (15 catheters) there were 14 events of systemic infections; seven events were treated successfully with antibiotics, four events necessitated the extraction of the catheter (in one patient a combination of systemic and local infection), and in three events the catheters were kept unused, as the patients were in terminal stages. Nonsystemic complications occurred with five catheters; two local infections, two obstructions (catheters removed), and one local bleeding (catheter kept unused). Appropriate antimicrobial treatment of systemic infections enables the immunocompromised child to keep the Port-A-Cath in place for a long time.