Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Late relapses in acute lymphoblastic leukemia.

L Russell1, O B Eden

  • 1Department of Haematology, Royal Hospital for Sick Children, Edinburgh, Scotland.

Pediatric Hematology and Oncology
|January 1, 1989
PubMed
Summary

Late relapses of acute lymphoblastic leukemia (ALL) are rare, occurring years after treatment stops. These unusual cases suggest the leukemia may be recurring rather than a new cancer forming.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Observation of tWZ Production at the CMS Experiment.

Physical review letters·2026
Same author

First Exclusive Reconstruction of the B^{*+}, B^{*0}, and B_{s}^{*0} Mesons and Precise Measurement of Their Masses.

Physical review letters·2026
Same author

Simultaneous Probe of the Charm and Bottom Quark Yukawa Couplings Using tt[over ¯]H Events.

Physical review letters·2026

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Leukemia Research

Background:

  • Acute lymphoblastic leukemia (ALL) is a common childhood cancer.
  • Maintenance therapy is standard after initial ALL treatment.
  • Long-term remission is the goal, but late relapses are possible.

Observation:

  • Two pediatric patients presented with relapsed ALL.
  • Relapses occurred 6 and 8 years after stopping maintenance therapy.
  • Such late relapses are exceptionally rare, with few documented cases.

Findings:

  • The study investigated the nature of these late relapses.
  • Genetic analysis suggested the relapsed leukemia was the original disease.
  • This challenges the notion of secondary leukemia in these instances.

Implications:

  • Understanding the biology of late ALL relapses is crucial.
  • This may impact long-term monitoring strategies for childhood leukemia survivors.
  • Further research is needed to elucidate mechanisms of late relapse.

Related Experiment Videos