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Updated: Apr 1, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Carotid Artery Stenting-Historical Context, Trends, and Innovations
Miloslav Spacek1, Josef Veselka1
1Department of Cardiology, University Hospital Motol, 2nd Medical School, Charles University, Prague, Czech Republic.
Insights
Carotid artery stenting (CAS) is now a reliable alternative to surgical carotid endarterectomy (CEA) for preventing strokes. This review covers CAS history, trends, and innovations in treating carotid artery disease.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Carotid endarterectomy (CEA) was the standard for severe carotid artery disease.
- Carotid artery stenting (CAS) was initially for high-risk patients due to technical challenges.
- Both procedures aim for primary and secondary stroke prevention.
Purpose of the Study:
- To review the historical development of carotid artery stenting (CAS).
- To discuss current trends and innovations in CAS.
- To position CAS as an alternative to CEA.
Main Methods:
- Literature review focusing on historical data.
- Analysis of trends in CAS adoption and outcomes.
- Examination of technological innovations in CAS devices and techniques.
Main Results:
- CAS has evolved from a high-risk procedure to a reliable alternative to CEA.
- Technological advancements have improved CAS safety and efficacy.
- CAS is increasingly considered for a broader patient population.
Conclusions:
- CAS is a viable and evolving treatment option for severe carotid artery disease.
- Innovations continue to enhance the role of CAS in stroke prevention.
- The choice between CAS and CEA depends on patient-specific factors and evolving evidence.
Abstract:
Surgical carotid endarterectomy (CEA) has been proven effective in both primary and secondary stroke prevention and, until recently, has been considered the standard treatment approach for patients with severe carotid artery disease. Because of its technical limitations and less favorable outcomes, carotid artery stenting (CAS) has been offered preferably to patients considered to be too comorbid to undergo surgical treatment. However, CAS has evolved over time into a reliable method and is currently considered an alternative to CEA. The aim of this review was to discuss the historical aspects, trends, and innovations in CAS.
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