Fibromuscular Dysplasia of Renal and Carotid Arteries
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Updated: Apr 1, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
Denisa Jahnlova1, Josef Veselka1
1Department of Cardiology, Charles University in Prague, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.
Abstract:
We report here two cases of fibromuscular dysplasia (FMD). The first case describes an asymptomatic 75-year-old man with FMD of the right internal carotid artery. The second case reports a 17-year-old man who presented with arterial hypertension caused by FMD of the left renal artery and was subsequently successfully treated by angioplasty. FMD is a rare nonatherosclerotic, noninflammatory angiopathy, which can involve almost every arterial vascular bed. It is a less common cause of stenosis of renal and carotid arteries. FMD can present with arterial hypertension when it involves renal arteries or with ischemic stroke or transient ischemic attack when the disease affects the carotid or vertebral arteries. Many cases are asymptomatic and may be discovered incidentally. Percutaneous transluminal angioplasty should be used in patients with a stenosis of the renal artery causing arterial hypertension. On the contrary, conservative therapy should be chosen in patients with asymptomatic and extensive lesions of the carotid arteries.
Insights
Fibromuscular dysplasia (FMD) can affect various arteries, leading to conditions like hypertension or stroke. Early diagnosis and appropriate treatment, such as angioplasty for renal artery stenosis, are crucial for managing FMD.
Area of Science:
- Vascular Medicine
- Radiology
Background:
- Fibromuscular dysplasia (FMD) is a rare, non-atherosclerotic, non-inflammatory condition affecting arterial walls.
- It can impact multiple arterial beds, including renal and carotid arteries.
Observation:
- Two cases of FMD are presented: an asymptomatic 75-year-old man with carotid artery FMD and a 17-year-old male with renal artery FMD causing hypertension.
- The latter case was successfully treated with angioplasty.
Findings:
- FMD can manifest as arterial hypertension (renal artery involvement) or cerebrovascular events like stroke or transient ischemic attack (carotid/vertebral artery involvement).
- Many FMD cases are asymptomatic and incidentally discovered.
Implications:
- Percutaneous transluminal angioplasty is recommended for renal artery stenosis causing hypertension.
- Conservative management is advised for asymptomatic, extensive carotid artery FMD lesions.
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