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Updated: Apr 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

Microneedles: bench to bedside.

Chandra Sekhar Kolli¹

¹Department of Pharmaceutical & Biomedical Sciences, California Health Sciences University, 120 N Clovis Avenue, Clovis, CA, US.

Therapeutic Delivery

|October 1, 2015

Summary

This summary is machine-generated.

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Microneedles are tiny skin structures that create microchannels for enhanced drug delivery. This technology enables the transdermal delivery of various molecules, including vaccines and diagnostics, with products now available on the market.

Area of Science:

Biomedical Engineering
Dermatology
Pharmaceutics

Background:

Microneedles are micron-sized structures designed for minimally invasive skin disruption.
They breach the stratum corneum without reaching pain-sensing nerves.
This creates aqueous microchannels for molecule delivery.

Purpose of the Study:

To summarize the advancements and applications of microneedle technology for transdermal drug delivery.

Main Methods:

Review of microneedle technology development and applications.
Discussion of material science and design considerations for microneedles.
Analysis of the types of molecules successfully delivered via microneedles.

Main Results:

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Last Updated: Apr 1, 2026

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

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Microneedles facilitate the delivery of diverse molecules, including small molecules, proteins, vaccines, and diagnostic agents.
The technology has evolved significantly from early metal and silicon designs.
Current microneedle products are available in the market.

Conclusions:

Microneedle technology offers a versatile platform for enhanced transdermal delivery.
It enables the efficient delivery of a wide range of therapeutic and diagnostic agents.
The commercial availability of microneedle products signifies technological maturity and clinical acceptance.