Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Highlights from SelectBio 2015: Academic Drug Discovery Conference, Cambridge, UK, 19-20 May 2015.

John Spencer1, Hannah Coaker2

  • 1Department of Chemistry, School of Life Sciences, University of Sussex, BN19QJ, UK.

Future Medicinal Chemistry
|October 1, 2015
PubMed
Summary

Related Concept Videos

Drug Discovery: Overview01:26

Drug Discovery: Overview

13.3K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
13.3K
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

84
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
84

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>In vitro</i> screening of compounds for targeting gastric cancer with Y220C p53 mutation: a molecule combining zinc chelation and a Michael acceptor drives <i>CDKN1</i> and <i>BBC3</i> expression to restore a p53-dependent cytotoxicity.

Journal of enzyme inhibition and medicinal chemistry·2026
Same author

Synthesis of N-Acetyl-D- and -L-Leucine-<sup>13</sup>C<sub>6</sub> Tool Compounds in Neurodegenerative Disease.

ChemMedChem·2026
Same author

Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt.

Cell death & disease·2026
Same author

The dihydropyridine LA1011 modulates multiple Hsp90-co-chaperone interactions relevant to Alzheimer's disease.

Cell stress & chaperones·2025
Same author

Removal of Toxic Metabolites-Chelation: Manganese Disorders.

Journal of inherited metabolic disease·2025
Same author

The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells.

Nature communications·2025

The SelectBio 2015 conference highlighted academic drug discovery research and its commercial applications. Experts discussed novel approaches and academic-industry partnerships, debating phenotypic versus targeted discovery strategies.

Area of Science:

  • Drug Discovery and Development
  • Biotechnology
  • Pharmaceutical Research

Background:

  • The SelectBio 2015 conference convened in Cambridge, UK, to advance academic drug discovery.
  • The event aimed to bridge the gap between basic scientific research and commercial pharmaceutical applications.
  • It built upon the success of previous academic drug discovery events held in the USA.

Framework:

  • Showcasing novel research from academic drug discovery programs.
  • Facilitating discussions on academic-industry partnerships and collaborations.
  • Exploring diverse therapeutic areas and innovative drug discovery methodologies.

Implementation:

  • Presentations by leading researchers, including Susanne Muller-Knapp and Julian Blagg.
  • Case studies illustrating successful academic-industry collaborations.
Keywords:
cancerchemical librarieschemical probesfragment-based drug discoveryhigh-throughput screeningprotein–protein interactions

Related Experiment Videos

  • A panel discussion debating phenotypic versus targeted drug discovery approaches.
  • Implications:

    • Fostering innovation in early-stage drug discovery.
    • Enhancing the translation of academic research into clinical applications.
    • Informing future strategies for drug development partnerships and methodologies.