Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peripheral nerve function in children with end-stage renal failure.

C E de Beaufort1, J L André, J J Heimans

  • 1Department of Paediatrics I, CHU Brabois, Nancy, France.

Pediatric Nephrology (Berlin, Germany)
|April 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic Accuracy of Neuroimaging to Delineate Diffuse Gliomas within the Brain: A Meta-Analysis.

AJNR. American journal of neuroradiology·2017
Same author

Prognostic value of the S100B protein in newly diagnosed and recurrent glioma patients: a serial analysis.

Journal of neuro-oncology·2016
Same author

Seasonal variation in month of diagnosis in children with type 1 diabetes registered in 23 European centers during 1989-2008: little short-term influence of sunshine hours or average temperature.

Pediatric diabetes·2014
Same author

Symptoms and medication management in the end of life phase of high-grade glioma patients.

Journal of neuro-oncology·2014
Same author

End of life care in high-grade glioma patients in three European countries: a comparative study.

Journal of neuro-oncology·2014
Same author

Central neurotoxicity of standard treatment in patients with newly-diagnosed high-grade glioma: a prospective longitudinal study.

Journal of neuro-oncology·2013

No clinical or subclinical peripheral neuropathy was found in children with end-stage renal failure (ESRF). However, haemodialysis may influence cutaneous sensation, warranting further investigation for early neuropathy screening.

Area of Science:

  • Pediatric Nephrology
  • Neurology

Background:

  • Peripheral neuropathy is a potential complication in children with end-stage renal failure (ESRF).
  • Limited data exists on the prevalence and detection of neuropathy in this pediatric population.

Purpose of the Study:

  • To investigate clinical and subclinical peripheral neuropathy in children with ESRF.
  • To compare non-invasive sensory testing (thermal discrimination threshold [TDT] and vibration perception threshold [VPT]) with nerve conduction velocity (NCV) measurements.

Main Methods:

  • Twelve children undergoing haemodialysis for ESRF were assessed.
  • TDT and VPT were measured twice before and after haemodialysis.
  • Peroneal nerve conduction velocity was measured once before haemodialysis.

Related Experiment Videos

Main Results:

  • No clinical or subclinical peripheral neuropathy was detected in any participant.
  • Most TDT and VPT results were within normal limits, with minor post-haemodialysis TDT elevations in two children.
  • No significant correlation was found between neuropathy indicators, age, or haemodialysis duration.
  • VPT showed a significant improvement post-haemodialysis, despite normal baseline values.

Conclusions:

  • Current non-invasive methods did not reveal neuropathy in pediatric ESRF patients.
  • Haemodialysis appears to influence cutaneous sensation, suggesting potential benefits.
  • Longitudinal studies are needed to validate TDT and VPT for early neuropathy screening in pediatric ESRF.