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Upper non-variceal gastrointestinal bleeding - review the effectiveness of endoscopic hemostasis methods

Mirosław Szura1, Artur Pasternak1

  • 1Mirosław Szura, Artur Pasternak, First Department, General, Oncological and Gastrointestinal Surgery, Jagiellonian University Medical College, 31-501 Krakow, Poland.

World Journal of Gastrointestinal Endoscopy
|October 1, 2015
PubMed

Insights

Upper gastrointestinal bleeding, often caused by peptic ulcers, has a high mortality rate. Early endoscopic hemostasis is crucial for reducing complications and improving patient outcomes in non-variceal bleeding cases.

Area of Science:

  • Gastroenterology
  • Endoscopic interventions
  • Internal Medicine

Background:

  • Upper non-variceal gastrointestinal bleeding presents a significant medical emergency with high mortality.
  • Peptic ulcers are the predominant cause, linked to Helicobacter pylori, NSAIDs, and aspirin use.
  • Effective hemostasis is critical for patient survival and reducing healthcare burden.

Purpose of the Study:

  • To review and compare the efficacy of various endoscopic hemostasis techniques for upper non-variceal gastrointestinal bleeding.
  • To synthesize current literature on the effectiveness of different endoscopic interventions.
  • To provide evidence-based insights for clinical decision-making.

Main Methods:

  • Systematic literature review and data pooling.
  • Comparative analysis of commonly used endoscopic hemostasis modalities.
  • Inclusion of studies focusing on non-variceal upper gastrointestinal bleeding.

Main Results:

  • Endoscopic therapy is the recommended first-line treatment, reducing re-bleeding, surgery, and mortality.
  • Early endoscopy (within 24 hours) significantly impacts hospital stay and transfusion needs.
  • Specific endoscopic hemostasis techniques demonstrate varying degrees of efficacy.

Conclusions:

  • Endoscopic hemostasis is vital for managing upper non-variceal gastrointestinal bleeding.
  • Timely endoscopic intervention improves clinical outcomes and resource utilization.
  • Further comparative studies are needed to optimize technique selection.

Keywords:
Endoscopic hemostasisEndoscopic therapyNon-variceal bleedingUpper gastrointestinal bleeding

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