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Electronic cigarette solutions and resultant aerosol profiles.

Jason S Herrington1, Colton Myers2

  • 1Restek Corporation, 110 Benner Circle, Bellefonte, PA 16823, United States.

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|October 1, 2015
PubMed
Summary

Electronic cigarette aerosol contains over 115 compounds, including harmful chemicals like formaldehyde, not found in the original e-liquid. This highlights significant differences between e-cigarette solutions and their resulting aerosol, impacting health assessments.

Keywords:
AerosolE-cigaretteElectronic cigaretteThermal desorptionVapor

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Area of Science:

  • Environmental Chemistry
  • Analytical Chemistry
  • Toxicology

Background:

  • Electronic cigarettes (e-cigarettes) are increasingly popular globally.
  • The chemical composition of e-cigarette aerosol remains incompletely understood.
  • Characterizing e-cigarette aerosol is crucial for assessing potential health risks.

Purpose of the Study:

  • To compare the chemical profiles of e-cigarette solutions and their generated aerosol.
  • To identify volatile organic compounds (VOCs) and semivolatile organic compounds (SVOCs) in e-cigarette aerosol.
  • To investigate potential formation of new compounds during the aerosolization process.

Main Methods:

  • Developed a novel sampling device for collecting e-cigarette aerosol onto thermal desorption (TD) tubes.
  • Analyzed aerosol and e-liquid samples using gas chromatography-mass spectrometry (GC-MS).
  • Compared chemical profiles of four commercial e-cigarette products in both liquid and aerosol phases.

Main Results:

  • Identified over 115 VOCs and SVOCs in e-cigarette aerosol from a single 40mL puff.
  • Detected over 82 compounds in aerosol profiles versus 64 in solution profiles.
  • Observed significant differences between liquid and aerosol analyte profiles, with compounds like formaldehyde, acetaldehyde, acrolein, and siloxanes present in aerosol but not in solutions.

Conclusions:

  • The aerosolization process in e-cigarettes can generate compounds not present in the original e-liquid.
  • These findings have significant implications for human health risk assessment related to e-cigarette use.
  • Emphasizes the critical need for comprehensive testing of e-cigarette aerosol, not just the liquid solutions.