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Flow cytometry in immunoglobulin light chain amyloidosis: Short review

Jana Filipova1, Lucie Rihova2, Pavla Vsianska2

  • 1Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic; Faculty of Science, University of Ostrava, Ostrava, Czech Republic.

Leukemia Research
|October 1, 2015
PubMed

Keywords:
AL amyloidosisFlow cytometryMonoclonal gammopathyPlasma cell

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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