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Updated: Apr 1, 2026
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O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
Published on: November 8, 2019
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[Validity of Near-infrared Spectroscopy]
Masui. the Japanese Journal of Anesthesiology
|October 2, 2015
Summary
Regional cerebral oxygen saturation (rSO2) monitoring is clinically used, but its accuracy is questioned. This review clarifies the issues and clinical usefulness of rSO2 measurements in patient care.
Area of Science:
- Biomedical Engineering
- Neurosurgery
- Anesthesiology
Background:
- Regional cerebral oxygen saturation (rSO2) is measured using near-infrared spectroscopy (NIRS).
- Clinical applications of rSO2 monitoring have been reported in cardiac and neurosurgery.
- Concerns exist regarding the accuracy of rSO2 values due to extra-cerebral contamination and optical path-length instability.
Purpose of the Study:
- To review and clarify the issues affecting the accuracy of rSO2 measurements.
- To evaluate the clinical usefulness of rSO2 monitoring.
Main Methods:
- Literature review of studies on rSO2 measurement accuracy and clinical application.
- Analysis of factors influencing rSO2 readings, including extra-cerebral contamination and optical path-length.
Main Results:
- Accuracy of rSO2 values is potentially compromised by physiological and technical factors.
- Despite limitations, rSO2 monitoring may offer valuable insights in specific clinical contexts.
Conclusions:
- Further research is needed to refine rSO2 measurement techniques and validate its clinical utility.
- Understanding the limitations of rSO2 is crucial for accurate interpretation in surgical settings.
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