Related Experiment Video
Updated: Apr 1, 2026

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
Published on: May 19, 2020
Childhood immunisation in Bungoma County, Kenya, from 2008 to 2011: need for improved uptake
G W Mbuthia1, A D Harries2, A A Obala1
1College of Health Sciences, Moi University, Eldoret, Kenya.
Insights
Childhood immunisation rates in Bungoma County, Kenya, significantly declined between 2008-2011. This drop in vaccine uptake raises concerns for potential outbreaks of preventable diseases.
Area of Science:
- Public Health
- Epidemiology
- Pediatrics
Background:
- Childhood immunisation is crucial for preventing infectious diseases.
- Monitoring vaccine uptake is essential for public health surveillance.
- Declining immunisation rates pose a significant public health risk.
Purpose of the Study:
- To determine immunisation uptake in children aged 1-2 years in Bungoma County, Kenya.
- To analyze trends in childhood immunisation coverage over a defined period.
- To identify potential declines in vaccine uptake and their implications.
Main Methods:
- Utilized data from 6-monthly Health and Demographic Surveillance System surveys.
- Assessed 2699 children in Bungoma County between 2008 and 2011.
- Analyzed trends in full immunisation and specific vaccine uptake (measles, oral polio, pentavalent).
Main Results:
- Full immunisation coverage significantly decreased from 84% to 58% (P < 0.001).
- Measles vaccine uptake declined from 89% to 60% (P < 0.001).
- Significant annual decreases were observed for third doses of oral polio and pentavalent vaccines (P < 0.001).
Conclusions:
- The study highlights a concerning decline in childhood immunisation in Bungoma County.
- Low immunisation coverage increases the risk of vaccine-preventable disease outbreaks.
- Further research is needed to understand the drivers behind these declining immunisation trends.
Abstract:
Uptake of immunisations in children aged 1-2 years in Bungoma County, Kenya, was determined as part of the 6-monthly Health and Demographic Surveillance System surveys. A total of 2699 children were assessed between 2008 and 2011. During this time period, full immunisation declined significantly from 84% to 58%, and measles vaccine declined uptake from 89% to 60% (P < 0.001). Each year there was a significant fall-off for the third doses of the oral polio and pentavalent vaccines (P < 0.001). These findings are of concern, as low immunisation coverage may lead to vaccine-preventable disease outbreaks. Further investigations into the reasons for declining immunisation trends are required.
More Related Videos
13:00Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
Published on: July 31, 2021
09:37Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
Related Concept Videos
Vaccinations
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Drug Dosing: Infants and Children
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Excretion