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Retrovirus Life Cycles

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...

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Related Experiment Video

Updated: Apr 1, 2026

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing

Published on: January 22, 2019

Tentative first steps to eradicate latent HIV

Stephen J Kent¹, Miles P Davenport²

¹Department of Microbiology and Immunology, The University of Melbourne, Peter Doherty Institute for Infection and Immunity, VIC 3010, Australia.

The Lancet. HIV

|October 2, 2015

Summary

No abstract available in PubMed .

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