Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

9.1K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
9.1K
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

656
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
656
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

4.8K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
4.8K
Glomerular Filtration01:15

Glomerular Filtration

7.2K
The filtration membrane in the renal system is a highly specialized structure essential for filtering blood. It consists of glomerular capillaries and podocytes, forming a selective barrier that permits the passage of water and small solutes while restricting most plasma proteins and blood cells.
Components of the Filtration Membrane
The filtration process involves three key layers: the glomerular endothelial cells, the basement membrane, and the podocyte-formed filtration slits.
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

OCT-Defined Foveal Restoration Is Associated with Visual Recovery after Vitrectomy for Lamellar Macular Hole: A Multicenter Study: LMH Report No. 1.

Ophthalmology. Retina·2026
Same author

Cyclin-dependent kinase 10 controls bone formation and is linked to human skeletal health.

Journal of orthopaedic translation·2026
Same author

From pixels to pores: 3D-(im)printed hierarchically porous polymer monoliths.

iScience·2026
Same author

Identification of an episignature for the MEF2C-associated syndrome.

European journal of human genetics : EJHG·2025
Same author

Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition.

Nature communications·2025
Same author

Discovery of a DNA methylation episignature as a molecular biomarker for fetal alcohol syndrome.

Genetics in medicine : official journal of the American College of Medical Genetics·2025

Related Experiment Video

Updated: Apr 1, 2026

Author Spotlight: Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues
09:50

Author Spotlight: Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues

Published on: February 9, 2024

2.0K

Segmental HOG: new descriptor for glomerulus detection in kidney microscopy image.

Tsuyoshi Kato1,2, Raissa Relator3, Hayliang Ngouv3

  • 1Faculty of Science and Engineering, Gunma University, Kiryu-shi, Gunma, 376-8515, Japan. katotsu@cs.gunma-u.ac.jp.

BMC Bioinformatics
|October 2, 2015
PubMed
Summary

A new Segmental Histogram of Oriented Gradients (HOG) descriptor improves glomeruli detection in kidney histopathology images. This method overcomes challenges from size, shape, and staining variations, offering better accuracy than Rectangular HOG.

More Related Videos

Optical Clearing and Imaging of Immunolabeled Kidney Tissue
06:18

Optical Clearing and Imaging of Immunolabeled Kidney Tissue

Published on: July 22, 2019

11.1K
Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes
11:47

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Published on: March 4, 2022

2.7K

Related Experiment Videos

Last Updated: Apr 1, 2026

Author Spotlight: Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues
09:50

Author Spotlight: Aiding Research in Kidney Biology by Labeling Glomeruli in Cleared Tissues

Published on: February 9, 2024

2.0K
Optical Clearing and Imaging of Immunolabeled Kidney Tissue
06:18

Optical Clearing and Imaging of Immunolabeled Kidney Tissue

Published on: July 22, 2019

11.1K
Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes
11:47

Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes

Published on: March 4, 2022

2.7K

Area of Science:

  • Nephropathology
  • Computational Pathology
  • Image Analysis

Background:

  • Glomeruli detection is crucial for kidney histopathology.
  • Variations in size, shape, and staining intensity pose detection challenges.
  • Existing methods like Rectangular HOG yield high false positives.

Purpose of the Study:

  • To develop an improved descriptor for accurate glomeruli detection in whole kidney sections.
  • To enhance robustness against variations in image characteristics.

Main Methods:

  • Development of a novel Segmental Histogram of Oriented Gradients (HOG) descriptor.
  • Utilizing flexible, adaptive blocks for descriptor fitting.
  • Implementation of a novel segmentation technique ensuring convergence to optimal solutions.

Main Results:

  • Segmental HOG demonstrates robust glomeruli detection across varied image conditions.
  • Achieved significant improvements in detection performance compared to Rectangular HOG.
  • High-quality segmentation outputs were generated.

Conclusions:

  • The proposed Segmental HOG descriptor shows significant promise for automated glomeruli detection.
  • Expected to be a valuable tool in pathological evaluation of kidney images.