Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

6.0K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.0K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.5K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.8K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.8K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

1.5K
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.5K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

4.4K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.4K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

15.0K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
15.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Delayed maturation of the milk microbiome in women with type 1 diabetes.

Diabetologia·2026
Same author

Glycaemic penalty index as an independent predictor of healthcare-associated infection in surgical inpatients: A nested cohort study from the STOIC-D surgery trial.

Diabetic medicine : a journal of the British Diabetic Association·2026
Same author

Real-world performance of point-of-care metre, blood gas and laboratory glucose methods in Australian and American hospital inpatient cohorts.

Diabetic medicine : a journal of the British Diabetic Association·2026
Same author

Reply.

Ophthalmology·2026
Same author

Higher HbA1c Following Younger Age of Transfer From Pediatric to Adult Type 1 Diabetes Services: Data From the Australasian Diabetes Data Network (ADDN) Registry.

Diabetes care·2026
Same author

A retrospective sub-study of perioperative glycaemia and insulin treatment for hospital inpatients at a quaternary centre from the specialist treatment of inpatients: Caring for diabetes in surgery trial (STOIC-D Surgery).

Diabetic medicine : a journal of the British Diabetic Association·2026
Same journal

Responding to the Revised First Nations Health and Cultural Safety Accreditation Standards in Australian Primary Medical Education: Institutional Principles and Qualities for Meaningful Progress.

The Medical journal of Australia·2026
Same journal

Multimorbidity Clusters Among People Aged 65 Years and Over in Australia: A Nationwide Cross-Sectional Data Linkage Study.

The Medical journal of Australia·2026
Same journal

Reducing Nitrous Oxide Emissions Across the Melbourne Biomedical Precinct.

The Medical journal of Australia·2026
Same journal

Still Treating Yesterday's Risk? Reconsidering Antiviral Use for Mild-to-Moderate COVID-19 Cases in a Broadly Immune Population.

The Medical journal of Australia·2026
Same journal

Striving for Racial Equity in Oral Cancer Research: A Case Study.

The Medical journal of Australia·2026
Same journal

Progressing Cross-Sector Collaboration for People With Eating Disorders and Higher Weight: Priority Actions From an Expert Roundtable Using a Modified Nominal Group Technique.

The Medical journal of Australia·2026
See all related articles

Related Experiment Video

Updated: Apr 1, 2026

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms
08:16

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms

Published on: March 15, 2024

2.3K

Recent advances in type 1 diabetes.

Mervyn Kyi1, John M Wentworth2, Alison J Nankervis2

  • 1Royal Melbourne Hospital, Melbourne, VIC peter.colman@mh.org.au.

The Medical Journal of Australia
|October 2, 2015
PubMed
Summary
This summary is machine-generated.

Type 1 diabetes (T1D) management is complex but improving with new technologies and personalized care. Advances in treatment and monitoring are enhancing glycaemic control and reducing risks for individuals with T1D.

More Related Videos

Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
10:09

Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets

Published on: May 11, 2015

10.2K
Bioluminescent Monitoring of Graft Survival in an Adoptive Transfer Model of Autoimmune Diabetes in Mice
10:03

Bioluminescent Monitoring of Graft Survival in an Adoptive Transfer Model of Autoimmune Diabetes in Mice

Published on: November 18, 2022

2.4K

Related Experiment Videos

Last Updated: Apr 1, 2026

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms
08:16

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms

Published on: March 15, 2024

2.3K
Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
10:09

Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets

Published on: May 11, 2015

10.2K
Bioluminescent Monitoring of Graft Survival in an Adoptive Transfer Model of Autoimmune Diabetes in Mice
10:03

Bioluminescent Monitoring of Graft Survival in an Adoptive Transfer Model of Autoimmune Diabetes in Mice

Published on: November 18, 2022

2.4K

Area of Science:

  • Endocrinology and Immunology
  • Metabolic Diseases
  • Autoimmune Disorders

Background:

  • Type 1 diabetes (T1D) results from autoimmune destruction of pancreatic beta cells, leading to insulin deficiency.
  • T1D incidence is rising globally, with a doubling in Australia over two decades.
  • Current management focuses on insulin replacement, but hypoglycaemia remains a significant risk.

Purpose of the Study:

  • To review current T1D management strategies and emerging technologies.
  • To highlight the importance of patient empowerment in diabetes self-management.
  • To discuss advancements in T1D prevention, treatment, and life expectancy.

Main Methods:

  • Review of current literature on T1D management, technology, and research.
  • Analysis of trends in T1D incidence and outcomes.
  • Discussion of therapeutic options including technology, transplantation, and future prevention strategies.

Main Results:

  • New technologies like insulin pumps and continuous glucose monitors improve glycaemic control and reduce hypoglycaemia.
  • Intensive glycaemic control and pregnancy planning improve outcomes for pregnant women with T1D.
  • Ongoing research aims to identify T1D determinants and develop preventative therapies.
  • Life expectancy for individuals with T1D has significantly improved, though premature mortality remains a concern.

Conclusions:

  • Optimizing T1D management requires a multifaceted approach, integrating technology and patient empowerment.
  • Advances in monitoring and treatment offer better control and reduced complications.
  • Future research holds promise for T1D prevention and improved long-term outcomes.