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Related Concept Videos

Brain Imaging01:14

Brain Imaging

948
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
948

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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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Structural brain alterations in hemifacial spasm: A voxel-based morphometry and diffusion tensor imaging study.

Ye Tu1, Tian Yu2, Yongxu Wei3

  • 1Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; Department of Anesthesiology, Zunyi Medical College, Zunyi 563003, China.

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|October 2, 2015
PubMed
Summary
This summary is machine-generated.

Hemifacial spasm (HFS) is linked to structural brain changes, specifically in gray matter volume, suggesting neuroplasticity in this chronic condition. No white matter disruptions were found.

Keywords:
Diffusion tensor imagingHemifacial spasmTract-based spatial statisticsVoxel-based morphometry

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Area of Science:

  • Neuroimaging
  • Neurology
  • Neuroscience

Background:

  • Hemifacial spasm (HFS) involves involuntary facial muscle movements due to facial nerve dysfunction.
  • Understanding the underlying brain structural changes in HFS is crucial for diagnosis and treatment.

Purpose of the Study:

  • To evaluate structural reorganization in brain gray matter and white matter in HFS patients.
  • To investigate the link between neuroplasticity and clinical features of HFS.

Main Methods:

  • Acquired high-resolution MRI and diffusion tensor imaging data from 42 HFS patients and 30 healthy controls.
  • Utilized voxel-based morphometry (VBM) for regional gray matter volume (GMV) analysis.
  • Employed tract-based spatial statistics (TBSS) to assess white matter microstructural integrity.

Main Results:

  • VBM revealed reduced GMV in the right inferior parietal lobule and increased GMV in cerebellar lobule VIII in HFS patients compared to controls.
  • Within the HFS group, decreased GMV in the right inferior parietal lobule correlated with longer disease duration.
  • TBSS analysis did not detect significant differences in white matter diffusivity parameters between groups.

Conclusions:

  • HFS is associated with significant gray matter volume alterations in brain regions involved in motor control.
  • No evidence of white matter integrity disruption was found in HFS patients.
  • These findings suggest structural reorganization in the brain is related to Hemifacial Spasm, a chronic neurovascular conflict disease.