Related Experiment Video
Updated: Apr 1, 2026

10:49
Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
Published on: September 18, 2011
21.3K
Cervical Myelopathy Caused by Injections into the Neck
Jeffrey W Ralph1, Rabia Malik1, Robert B Layzer1
1UCSF Medical Center, San Francisco, CA, USA.
The Neurohospitalist
|October 2, 2015
Summary
Neck injections can cause serious spinal cord injury, specifically longitudinally extensive cervical myelopathy. This rare complication should be considered following any deep neck injection procedure.
Area of Science:
- Neurology
- Neurosurgery
- Toxicology
Background:
- Reports of acute cervical myelopathy following neck injections have increased.
- Spinal cord injury presentation is consistent despite varied injection techniques and substances.
Purpose of the Study:
- To present three cases of longitudinally extensive cervical myelopathy temporally associated with neck injections.
- To discuss potential mechanisms causing this complication.
Main Methods:
- Case series presentation.
- Radiographic analysis of spinal cord injury.
- Discussion of proposed etiological mechanisms.
Main Results:
- All three cases demonstrated similar spinal cord injury patterns.
- Multiple injection approaches and substances were used across the cases.
Conclusions:
- Acute cervical myelopathy is a potential, albeit rare, complication of deep neck injections.
- Possible mechanisms include direct trauma, microvascular embolism, and intraneural injection with centripetal spread.
Keywords:
EMG/nerve conduction velocitybrachial plexus neuropathiesneuromuscular diseasesspinal cord diseasesspinal cord injuriestechniquesMore Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
1.9K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.9K
Drug Delivery: Parenteral Route
2.5K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
2.5K
Myasthenia Gravis: Overview and Treatment
3.4K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
3.4K

