Fever-Induced Brugada Syndrome

Area of Science:

• Cardiology
• Genetics
• Electrophysiology

Background:

• Brugada syndrome is a significant cause of sudden cardiac death.
• Diagnosis is challenging due to its dynamic and often concealed presentation.
• The electrophysiology is closely associated with sodium channel mutations or disorders.

Purpose of the Study:

• To highlight conditions that can reveal or potentiate Brugada syndrome arrhythmogenicity.
• To present a case where fever unmasked Brugada syndrome.

Main Methods:

• Case report presentation.
• Review of Brugada syndrome pathophysiology and triggers.

Main Results:

• Fever was identified as a precipitating factor for Brugada syndrome manifestation in the presented case.
• The patient's Brugada syndrome became evident under febrile conditions.

Conclusions:

• Clinicians must be aware of fever as a potential trigger for Brugada syndrome.
• Recognizing triggers is crucial for timely diagnosis and management of Brugada syndrome to prevent sudden cardiac death.