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Updated: Apr 1, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
Published on: September 13, 2013
In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis
Kalyan K Sadhu1, E Lindberg, N Winssinger
1University of Geneva, School of Chemistry and Biochemsitry, NCCR Chemical Biology, 30 quai Ernest Ansermet, Geneva, Switzerland. nicolas.winssinger@unige.ch.
Abstract:
Labelling of proteins with a luminescent ruthenium complex enables the direct visualization and photocatalytic reduction of aryl azide in live cells. The confinement of catalysis to the labeled proteins was visualized using an azide-based immolative linker releasing a precipitating dye.
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