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Gold-installed biostable nanocomplexes for tumor-targeted siRNA delivery in vivo
Roun Heo1, Hong Yeol Yoon, Hyewon Ko
1Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Suwon 440-746, Republic of Korea. jhpark1@skku.edu.
Abstract:
The key issues, associated with nanocarriers for small interfering RNAs (siRNAs), are their poor stability and lack of tumor targetability in vivo. To address these issues, we developed gold-installed polyethyleneimine/siRNA complexes with a corona of PEGylated hyaluronic acid.

