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Related Concept Videos

Nightmares and Night Terrors01:18

Nightmares and Night Terrors

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Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
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REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
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Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
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Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
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Ramelteon-induced nightmares: A case report.

Chintan Shah1, Anita Kablinger1

  • 1Department of Psychiatry & Behavioral Medicine, Carilion Clinic-Virginia Tech Carilion, First Floor Administrative Suites, 2017 South Jefferson Street, Roanoke 24014, VA, United States.

Asian Journal of Psychiatry
|October 3, 2015
PubMed
Summary
This summary is machine-generated.

Ramelteon, an insomnia medication, may cause vivid nightmares in some patients, a side effect not previously documented. These nightmares resolved after discontinuing the drug, suggesting a potential link.

Keywords:
DreamsNightmaresRamelteon

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Area of Science:

  • Pharmacology
  • Sleep Medicine
  • Neurology

Background:

  • Ramelteon is the sole FDA-approved melatonin receptor agonist for insomnia treatment.
  • It selectively targets melatonin MT1 and MT2 receptors, modulating sleep-wake cycles.

Observation:

  • A case study details a patient experiencing vivid nightmares shortly after starting ramelteon for insomnia disorder.
  • The patient discontinued ramelteon due to the nightmares, which subsequently resolved.

Findings:

  • This report documents the first known instance of nightmares potentially secondary to ramelteon use.
  • Ramelteon is generally well-tolerated with a favorable side-effect profile in most patients.

Implications:

  • Further research is needed to investigate ramelteon's effects on rapid eye movement (REM) sleep, the stage where dreaming occurs.
  • Clinicians should consider nightmares as a possible adverse effect of ramelteon, especially in susceptible individuals.