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Promoting Tdap immunization in pregnancy: Associations between maternal perceptions and vaccination rates
Nalin Payakachat1, Kristie B Hadden2, Denise Ragland1
1Department of Pharmacy Practice, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Providing a Tdap vaccine information statement (VIS) improved pregnant women's perception of the Tdap vaccine. Vaccination intention predicted Tdap vaccine uptake, highlighting the importance of educational materials for maternal immunization.
Area of Science:
- Public Health
- Vaccinology
- Health Communication
Background:
- Maternal Tdap (tetanus, diphtheria, and acellular pertussis) vaccination rates remain suboptimal in the US despite established recommendations.
- Low uptake may stem from insufficient understanding or perceived benefits of the vaccine during pregnancy.
Purpose of the Study:
- To assess the impact of a Tdap vaccine information statement (VIS) on pregnant women's perception, vaccination intention, and related health behavior model components.
- To evaluate if a standard VIS (sVIS) or a modified VIS (mVIS) differentially affected these outcomes.
Main Methods:
- A randomized prospective study involved pregnant women at two clinics who received either sVIS or mVIS before completing surveys.
- Health behavior models (Reasoned Action Approach, Health Belief Model) guided hypothesis formulation.
- Logistic regression, path analysis, and chi-square tests analyzed survey data and chart-reviewed vaccination status.
Main Results:
- Overall perception scores significantly increased post-VIS review (p<0.001).
- 47% of participants received the Tdap vaccine; no significant difference was observed between sVIS and mVIS groups.
- Perceived benefits, self-efficacy, and social norms were associated with perception and vaccination intention.
Conclusions:
- Vaccine information statements effectively enhance understanding and perception of the Tdap vaccine among pregnant women.
- Vaccination intention is a key predictor of actual Tdap vaccine uptake in this population.
- Educational interventions emphasizing immunization benefits are critical for promoting maternal Tdap vaccination.
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