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Mood instability: significance, definition and measurement
M R Broome1, K E A Saunders2, P J Harrison2
1M. R. Broome, PhD, MRCPsych, Department of Psychiatry, University of Oxford, Oxford, Oxford Health NHS Foundation Trust, Oxford and Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, Coventry; K. E. A. Saunders, DPhil, MRCPsych, P. J. Harrison, DM, FRCPsych, Department of Psychiatry, University of Oxford, Oxford; S. Marwaha, PhD, MRCPsych, Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, Coventry and Early Intervention Service, Swanswell Point, Coventry, UK matthew.broome@psych.ox.ac.uk.
Mood instability is a common psychiatric feature. Targeting mood instability may offer new treatment avenues across various disorders.
Area of Science:
- Psychiatry and Neuroscience
Background:
- Mood instability is prevalent and a key characteristic of numerous psychiatric conditions.
- Understanding its definition, measurement, and prevalence is crucial for clinical practice.
Discussion:
- This review explores the characteristics, neurobiological underpinnings, and clinical relevance of mood instability.
- It highlights the need for standardized assessment tools and further research into its mechanisms.
Key Insights:
- Mood instability presents significant challenges in diagnosing and treating psychiatric disorders.
- Neurobiological correlates suggest specific pathways involved in mood dysregulation.
Outlook:
- Mood instability holds considerable transdiagnostic potential as a target for novel investigations and therapies.
- Future research should focus on developing targeted interventions for mood instability to improve patient outcomes.
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