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Related Concept Videos

RNA-seq03:21

RNA-seq

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Sequencing of mRNA from Whole Blood using Nanopore Sequencing
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A vision for ubiquitous sequencing.

Yaniv Erlich1

  • 1Department of Computer Science, Columbia University, New York, New York 10027, USA; New York Genome Center, New York, New York 10013, USA.

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|October 3, 2015
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Summary
This summary is machine-generated.

The $1000 genome era has arrived, enabling affordable DNA sequencing. The next frontier is miniaturized sequencing sensors for real-time, widespread applications, though challenges remain for their development.

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Area of Science:

  • Genomics
  • Biotechnology
  • Sensor Technology

Background:

  • The $1000 genome milestone has been achieved, making whole genome sequencing affordable.
  • This success paves the way for the next phase of the sequencing revolution: portable sequencing sensors.

Purpose of the Study:

  • To envision diverse applications for decentralized sequencing sensors.
  • To identify critical barriers hindering the development of ubiquitous sequencing sensors.

Main Methods:

  • Conceptualization of real-time sequencing applications across various domains.
  • Analysis of technological and logistical challenges for sensor deployment.

Main Results:

  • Identified numerous potential applications benefiting from in-situ sequencing.
  • Outlined key obstacles in manufacturing, cost, and deployment for sequencing sensors.

Conclusions:

  • Sequencing sensors represent the next logical advancement in genomics.
  • Overcoming identified barriers is crucial for realizing the potential of widespread, low-cost sequencing technology.