Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

3.8K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
3.8K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

834
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
834
Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

1.1K
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
1.1K
Ventilatory Modes01:14

Ventilatory Modes

2.0K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
2.0K
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

998
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
998
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

2.6K
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Co-infection of Dengue and Malaria Complicated With Acute Respiratory Distress Syndrome (ARDS) in a Critically Ill Patient: A Case Report From a Tertiary Care Center in Jharkhand, India.

Cureus·2026
Same author

Lamotrigine and Fluoxetine Overdose Presenting With Severe Neuro-Cardiotoxicity: A Case Report.

Cureus·2026
Same author

Multi-omics and pan-cancer analysis revealed common molecular signatures to disclose multitargeted anticancer agents through network pharmacology approach.

PloS one·2026
Same author

Viability of dental implants in patients treated for oral squamous carcinoma: A retrospective study.

Journal of Indian Prosthodontic Society·2026
Same author

Preeclampsia Is a Double-Hit Vascular Disorder: The VEGF-HO-1-CSE Axis.

Biomolecules·2026
Same author

Timing of dental surgery in patients receiving bone-modifying agents: Medication related osteonecrosis of jaw (MRONJ) and implant outcomes in a cohort of 5,284 oncology patients within an integrated dental pathway.

Journal of clinical and experimental dentistry·2026

Related Experiment Video

Updated: Apr 1, 2026

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
04:56

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA

Published on: July 14, 2023

5.9K

Neonatal mechanical ventilation: Indications and outcome.

Qazi Iqbal1, Mir M Younus1, Asif Ahmed1

  • 1Department of Neonatology and Pediatrics, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|October 3, 2015
PubMed
Summary

Identifying risk factors for mortality in ventilated neonates is crucial. Factors like low birth weight, prematurity, and initial low pH independently predict mortality in sick newborns.

Keywords:
Complications of ventilationneonatal mechanical ventilationpredictors of mortality

More Related Videos

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

1.4K
The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.4K

Related Experiment Videos

Last Updated: Apr 1, 2026

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
04:56

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA

Published on: July 14, 2023

5.9K
3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

1.4K
The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
09:03

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation

Published on: August 15, 2018

11.4K

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care
  • Respiratory Physiology

Background:

  • High mortality rates in sick and mechanically ventilated neonates necessitate risk factor identification.
  • Understanding indications and complications of ventilation is key to improving outcomes.

Purpose of the Study:

  • To determine the indications for mechanical ventilation in neonates.
  • To identify complications associated with neonatal ventilation.
  • To investigate predictors of mortality in this vulnerable population.

Main Methods:

  • A cohort of 300 neonates requiring mechanical ventilation was studied.
  • Data collected included primary disease, complications, and clinical/laboratory parameters.
  • Logistic regression analysis identified independent predictors of mortality.

Main Results:

  • The most common indications for ventilation were respiratory distress syndrome (RDS), sepsis, and birth asphyxia.
  • Mortality rates were highest for sepsis (64.7%) and pneumonia (60%).
  • Independent predictors of mortality included prematurity (gestation <34 weeks), initial pH <7.1, pulmonary hemorrhage, and shock.

Conclusions:

  • Low birth weight (<2500 g) and prematurity (<34 weeks gestation) are significant risk factors.
  • Initial low arterial pH (<7.1), shock, and pulmonary hemorrhage are critical predictors of mortality.
  • Apnea, hypoglycemia, neutropenia, and thrombocytopenia also correlate with increased mortality risk.