Related Experiment Video
Updated: Apr 1, 2026

08:08
Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants
Published on: August 18, 2023
6.1K
Occupational lead toxicity in battery workers.
Shahla Basit1, Nasim Karim2, Alia Bano Munshi3
1Shahla Basit, MBBS Principal Medical Officer.
Pakistan Journal of Medical Sciences
|October 3, 2015
Summary
Lead acid battery workers in Karachi show high blood lead levels and symptoms of lead toxicity. This study highlights the prevalence of lead exposure and its health effects in this industrial group.
Area of Science:
- Occupational Health
- Environmental Toxicology
- Industrial Hygiene
Background:
- Lead exposure poses significant health risks, particularly in industrial settings.
- Lead acid battery manufacturing is a known source of occupational lead exposure.
- Understanding the extent of lead toxicity among these workers is crucial for public health.
Purpose of the Study:
- To determine blood lead levels (BLL) in lead acid battery (LAB) industrial workers.
- To identify and assess the clinical features of lead toxicity in this population.
- To establish the prevalence of elevated BLL and associated health issues.
Main Methods:
- Prospective study conducted from March 2012 to March 2013 in Karachi.
- Fifty LAB industry workers (17-65 years) divided into directly (n=40) and indirectly (n=10) exposed groups.
- Data collected via detailed history, physical examination, and blood lead level estimation using flameless atomic absorption spectrophotometry.
Main Results:
- Elevated BLL was found in 34 workers (group 1) and 3 workers (group 2).
- Group 1 workers exhibited higher prevalence of anemia, bone pain, abdominal pain, nausea, headache, irritability, weakness, lethargy, tremors, and hypertension.
- Lead line was observed in 4 directly exposed workers, and insomnia in 5 group 1 and 4 group 2 workers.
Conclusions:
- A high prevalence of elevated blood lead levels was observed among lead acid battery industry workers in Karachi.
- Clinical features consistent with lead toxicity were common in workers with direct exposure.
- The findings underscore the need for improved occupational safety measures and health surveillance in this industry.
Keywords:
Atomic Absorption spectrophotometerBlood Lead LevelLead ExposureLead ToxicityOccupational HealthMore Related Videos
Related Concept Videos
Types of Toxins
4.0K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
4.0K
Toxic Reactions: Overview
3.8K
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
3.8K
Toxicity Testing in Animals
140
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
140
The Periodic Table and Organismal Elements
23.6K
Elements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally occurring, and only a few of them are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.
Periodic Table Provides Information...
Periodic Table Provides Information...
23.6K
The Periodic Table and Organismal Elements
205.7K
OverviewElements are the smallest units of matter that cannot be broken down further by chemical processes. There are 118 known elements, but not all of these are naturally-occurring, and fewer still are essential for life. Living matter is composed primarily of carbon, nitrogen, hydrogen, and oxygen, with smaller amounts of other elements like calcium, phosphorus, potassium, and sulfur. Other elements are also necessary for life but only in trace amounts.The Periodic Table Provides Information...
205.7K
Toxidromes: Clinical Features
126
Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
126

