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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: Apr 1, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Radiation-Induced Intraspinal Chondrosarcoma: A Case Report.

Peter Obid¹, Mathias Vierbuchen², Eduard Wolf²

¹Department of Spinal and Scoliosis Surgery, Asklepios Klinik St. Georg, Hamburg, Germany.

Global Spine Journal

|October 3, 2015

Summary

This case report details a rare, aggressive radiation-induced chondrosarcoma diagnosed 18 years post-radiotherapy. Early, extensive surgery is crucial for long-term survival in these challenging tumors.

Area of Science:

Oncology
Neurosurgery
Radiotherapy

Background:

Radiation-induced sarcomas are rare but aggressive secondary malignancies.
Chondrosarcomas can develop years after radiation therapy.

Keywords:

chondrosarcoma intraspinal tumor radiation-induced sarcoma radiotherapy secondary malignancy

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