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Lipid-based nanocarriers for breast cancer treatment - comprehensive review

Siddartha Venkata Talluri1, Gowthamarajan Kuppusamy1, Veera Venkata Satyanarayana Reddy Karri1

  • 1a Department of Pharmaceutics , JSS College of Pharmacy, JSS University , Udhagamandalam , Tamil Nadu , India and.

Drug Delivery
|October 3, 2015
PubMed

Insights

Lipid nanoparticles show promise for breast cancer treatment, offering new therapeutic options. Further research is needed to scale up these nanomedicines for clinical use.

Area of Science:

  • Oncology
  • Nanotechnology
  • Drug Delivery

Background:

  • Breast cancer is a leading cause of cancer-related death in women.
  • Current breast cancer treatments have limitations and toxicities.
  • Nanotechnology offers potential for targeted breast cancer therapy.

Purpose of the Study:

  • To review recent advancements in lipid-based nanocarriers for breast cancer treatment.
  • To highlight the development of nanomedicines for enhanced therapeutic outcomes.

Main Methods:

  • Review of recently published studies on lipid nanoparticles for breast cancer.
  • Analysis of various lipid nanoparticle formulations including liposomes, SLNs, NLCs, and LPHNs.

Main Results:

  • Lipid nanoparticles demonstrate potential in targeting and treating breast cancer.
  • Various lipid-based nanocarrier systems have been developed for breast cancer therapy.
  • Current research is primarily at the laboratory scale.

Conclusions:

  • Lipid nanoparticles represent a promising area for breast cancer treatment development.
  • Translating lab-scale concepts to large-scale clinical applications is crucial.
  • Further development is needed to realize the full potential of nanomedicine in breast cancer care.
Keywords:
Breast cancerlipidlipid polymer hybrid nanoparticlesliposomesnanostructured lipid carrierssolid lipid nanoparticles

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