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Chemically induced dimerization: reversible and spatiotemporal control of protein function in cells

Stephanie Voß1, Laura Klewer1, Yao-Wen Wu1

  • 1Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Str. 15, 44227 Dortmund, Germany; Max Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.

Current Opinion in Chemical Biology
|October 4, 2015
PubMed
Summary

Chemically induced dimerization (CID) offers precise control over biological processes, surpassing traditional genetic methods. Advanced CID systems now enable detailed studies of signal transduction, membrane, and protein trafficking.

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