Vector representation and its application of DNA sequences based on nucleotide triplet codons
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Updated: Apr 1, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
FengLan Bai1, JiHong Zhang1, JunSheng Zheng2
1School of Science, Dalian Jiaotong University, Dalian 116028, China.
Abstract:
Compared with single nucleotide, nucleotide triplet appears to contain more biological and genetic information, so it has been applied widely. We propose a new 3D-vector representation method of DNA sequences, namely use molecular weight of nucleotide triplet to define the '0' molecular plane, then make the 3-D coordinate transformation to map a DNA sequence into a curve by the coordinate accumulation, and then extract the D/D matrix's eigenvalues to describe, compare and analyze the DNA sequences as the numerical characterization. It is a new idea for comparison and phylogenetic trees' reconstruction of biological sequences.
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