Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

2.1K
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
2.1K
Overview of Fungi01:29

Overview of Fungi

2.4K
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
2.4K
Antifungal Agents01:15

Antifungal Agents

53
Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
53
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

2.0K
Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
2.0K
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

2.4K
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
2.4K
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

716
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
716

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experimental human colonisation with non-toxigenic Clostridioides difficile: a placebo-controlled randomised clinical trial.

Nature communications·2026
Same author

Ultrasound dynamics during treatment of pulmonary and extra-pulmonary TB.

IJTLD open·2026
Same author

Development of a quantitative self-assessment tool for hospital antimicrobial stewardship and infection control programs: a step towards standardizing clinical studies.

JAC-antimicrobial resistance·2026
Same author

The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice.

Mycoses·2025
Same author

Molecular diagnostics in cancer patients with suspected respiratory mold infections.

Journal of clinical microbiology·2025
Same author

Health economic burden of refractory and recurrent Clostridioides difficile infection in the inpatient setting of the German healthcare system - the IBIS Study.

The Journal of hospital infection·2025

Related Experiment Video

Updated: Apr 1, 2026

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure
10:33

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure

Published on: May 27, 2022

7.4K

[Resistant fungi].

M J G T Vehreschild1,2, O A Cornely3,4,5

  • 1Klinisches Studienzentrum II für Infektiologie, Klinik I für Innere Medizin, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland. maria.vehreschild@uk-koeln.de.

Der Internist
|October 4, 2015
PubMed
Summary

Fungal infections in immunocompromised patients are a growing concern. Understanding antifungal resistance patterns in yeasts and molds is crucial for effective treatment strategies, especially in hematology/oncology and intensive care settings.

Keywords:
Antifungal agentsAzole resistanceFungal infections, rareMoldsYeasts

More Related Videos

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

6.1K
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K

Related Experiment Videos

Last Updated: Apr 1, 2026

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure
10:33

Isolation of Culturable Yeasts and Molds from Soils to Investigate Fungal Population Structure

Published on: May 27, 2022

7.4K
Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials
08:21

Isolation and Screening from Soil Biodiversity for Fungi Involved in the Degradation of Recalcitrant Materials

Published on: May 16, 2022

6.1K
Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K

Area of Science:

  • Mycology
  • Infectious Diseases
  • Clinical Medicine

Context:

  • Rising incidence of fungal infections in hematology/oncology and intensive care medicine.
  • Fungal resistance emergence impacts treatment strategies, though less dynamic than bacterial resistance.
  • Focus on key pathogens: Candida albicans, Aspergillus fumigatus, Mucorales, and Fusarium.

Purpose:

  • To present and discuss significant antifungal resistance patterns in clinically relevant yeasts and molds.
  • To highlight diagnostic and therapeutic challenges associated with fungal infections.
  • To provide guidance on adapting antifungal treatments based on resistance data and clinical presentation.

Summary:

  • Yeast resistance testing is typically available via blood cultures.
  • Mold infection management often relies on empirical antifungal therapy guided by CT scans.
  • Biopsies and surgical resection may be necessary for refractory mold infections, including mucormycosis.

Impact:

  • Improved clinical decision-making for antifungal therapy in high-risk patient populations.
  • Enhanced management of invasive fungal infections through tailored treatment approaches.
  • Potential for better patient outcomes by addressing challenging resistance mechanisms.