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Published on: September 16, 2025
Safety and efficacy of wavefront-guided myopic laser in situ keratomileusis using a new wavefront sensor technology:
David Smadja1, Marcony R Santhiago1, Joy Tellouck1
1From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
Purpose:
To evaluate the safety and efficacy of wavefront-guided laser in situ keratomileusis (LASIK) for the correction of low to high myopia and myopic astigmatism using data derived from a new-generation Hartmann-Shack aberrometer.
Setting:
Refractive Surgery Unit, Bordeaux Hospital University, France.
Design:
Retrospective case series.
Methods:
This retrospective study analyzed the initial group of eyes treated with wavefront-guided LASIK for myopia and myopic astigmatism using the Visx S4IR excimer laser and wavefront data derived from a new Hartmann-Shack aberrometer (iDesign Advanced Wavescan aberrometer). Refractive (refraction and refractive accuracy) and visual outcomes (uncorrected [UDVA] and corrected [CDVA] distance visual acuities) were recorded 3 months postoperatively.
Results:
The study included 100 eyes of 50 consecutively treated patients. The mean decimal UDVA improved from 0.1 ± 0.1 (SD) preoperatively to 1.1 ± 0.15 postoperatively (P < .01). A monocular UDVA of 20/16, 20/20, and 20/25 were achieved in 76.6%, 94.4%, and 96.6% of eyes, respectively. The postoperative manifest spherical equivalent was within ±0.5 diopter in all eyes. No eye lost 2 or more lines of CDVA, and 29.2% of the eyes gained 1 or more lines of CDVA.
Conclusion:
Wavefront-guided LASIK performed using data derived from the new Hartmann-Shack aberrometer was safe, effective, and predictable for treating myopia and myopic astigmatism.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.
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