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Published on: September 16, 2025
Comparability of anterior chamber depth measurements with partial coherence interferometry and optical low-coherence
Nikolaus Luft1, Nino Hirnschall1, Sanaz Farrokhi1
1From the Vienna Institute for Research in Ocular Surgery (Luft, Hirnschall, Farrokhi, Findl), A Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria; Moorfields Eye Hospital NHS Foundation Trust (Findl), London, United Kingdom.
Purpose:
To assess whether anterior chamber depth (ACD) measurements in pseudophakic eyes obtained with partial coherence interferometry (PCI) and optical low-coherence reflectometry (OLCR) devices can be used interchangeably.
Setting:
Vienna Institute for Research in Ocular Surgery, A Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria.
Design:
Prospective case series.
Methods:
The ACD measurements in 1 eye of each pseudophakic patient were performed with the PCI-based ACMaster device and the OLCR-based Lenstar LS900 device at least 1 day postoperatively.
Results:
The study comprised 65 eyes of 65 patients with a mean age of 71.7 years ± 9.0 (SD) (range 39 to 91 years). In 15 eyes, no valid ACD readings could be obtained with the OLCR device. No obvious reason for these measurement failures was identified; however, tear-film alterations shortly after surgery were suspected. No significant difference in the mean ACD in the remaining 50 eyes was found between PCI measurements (5019 ± 660 μm; range 4008 to 6181 μm) and OLCR measurements (5015 ± 663 μm; range 4017 to 6163 μm) (P = .06). Three (6%) of 50 measurements were not within the 95% limits of agreement in the Bland-Altman analysis.
Conclusions:
Pseudophakic ACD measurements with the PCI and OLCR devices can be used interchangeably. The OLCR device proved to be more user-friendly and faster; however, in a substantial number of eyes, no usable values were obtainable.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.

