Related Experiment Video
Updated: Aug 16, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
Changes in intraocular pressure after cataract surgery: analysis of the Swedish National Cataract Register Data
Charlotta Zetterström1, Anders Behndig1, Maria Kugelberg1
1From the Department of Clinical Neuroscience (Zetterström, Kugelberg, Montan), Division of Ophthalmology and Vision, Karolinska Institutet, and EyeNet Sweden (Zetterström, Lundström), Blekinge Hospital, Karolinska; St. Erik Eye Hospital (Kugelberg, Montan), Stockholm; the Department of Clinical Sciences/Ophthalmology (Behndig), Umeå University Hospital, Umeå; and the Department of Clinical Sciences (Lundström) Ophthalmology, Faculty of Medicine, Lund University, Lund, Sweden.
Purpose:
To analyze changes in intraocular pressure (IOP) after cataract surgery based on data from the Swedish National Cataract Register (NCR).
Setting:
Ophthalmic surgery units in Sweden.
Design:
Prospective database study.
Methods:
Data for 2012 through 2014 were obtained prospectively from the NCR. The outcome register of the NCR has collected data on IOP before and a mean of 37.7 days ± 29.1 (SD) after cataract surgery since 2012.
Results:
The analyses were based on 20 437 cataract extractions reported during 1 month each year to the outcome registry of the NCR. Cataract surgery was found to reduce IOP by a mean of 1.46 mm Hg, which was statistically significant (P < .001). A larger IOP reduction was seen in cases with a higher preoperative IOP (r = 0.557, P < .001). Older patients and shorter eyes had a greater IOP reduction after surgery (P < .001 and P = .001, respectively). Women had a greater IOP reduction than men (P = .04) When high IOP was given as an indication for surgery, the IOP reduction after cataract surgery was 5.50 mm Hg compared with a reduction of 1.40 mm Hg in patients for whom this indication was not given (P < .001). Patients with glaucoma or pseudoexfoliation (PXF) had a more pronounced IOP reduction than patients without these diagnoses (P < .001).
Conclusion:
Cataract surgery had an IOP-lowering effect, in particular in older patients, women, short eyes, eyes with high preoperative IOP, and eyes with glaucoma or PXF.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment

