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Updated: Apr 1, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
The Risk of a Deep Infection Associated With Intraarticular Injections Before a Total Knee Arthroplasty
Nirav H Amin1, Didi Omiyi2, Bozena Kuczynski2
1Loma Linda University, Loma Linda, California.
The aim of the study is to identify the risks associated with an intraarticular injection before a total knee arthroplasty (TKA). A total of 1628 patients were retrospectively studied over a 7-year period. The patients were divided into 2 groups: patient who received an intraarticular injection before a TKA and patients who did not receive an injection before a TKA. There were 16 deep infections identified (0.98%). Ten deep infections were identified in the patients who did not receive an injection before a TKA (1.18%), and 6 deep infections were identified in patients who received an injection before a TKA (0.77%). There does not appear to be a correlation with the timing of the injection before surgery and increased risk of infection.
The aim of the study is to identify the risks associated with an intraarticular injection before a total knee arthroplasty (TKA). A total of 1628 patients were retrospectively studied over a 7-year period. The patients were divided into 2 groups: patient who received an intraarticular injection before a TKA and patients who did not receive an injection before a TKA. There were 16 deep infections identified (0.98%). Ten deep infections were identified in the patients who did not receive an injection before a TKA (1.18%), and 6 deep infections were identified in patients who received an injection before a TKA (0.77%). There does not appear to be a correlation with the timing of the injection before surgery and increased risk of infection.
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