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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

681
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
681
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

584
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
584
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

577
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
577
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

618
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
618
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

629
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
629
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

418
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
418

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Related Experiment Video

Updated: Apr 1, 2026

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

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[Update peripheral arterial occlusive disease].

E Blessing1

  • 1SRH-Klinikum Karlsbad-Langensteinbach, Guttmannstr. 1, 76307, Karlsbad-Langensteinbach, Deutschland. erwin.blessing@kkl.srh.de.

Herz
|October 4, 2015
PubMed
Summary

Peripheral arterial occlusive disease (PAD) is common. Drug-eluting balloons significantly reduce restenosis after endovascular treatment, offering a promising strategy for managing PAD complications.

Keywords:
AtherosclerosisCoronary interventionIntermittent claudicationIschemiaPreventive measures

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Area of Science:

  • Vascular Medicine and Interventional Cardiology
  • Biomaterials and Drug Delivery Systems

Context:

  • Peripheral arterial occlusive disease (PAD) is a growing public health concern in industrialized nations due to demographic shifts.
  • Endovascular treatment approaches are increasingly favored for PAD management due to high success and low complication rates.
  • Restenosis, particularly in infrapopliteal arterial lesions, remains a significant limitation of endovascular interventions.

Purpose:

  • To review the current landscape of endovascular treatment strategies for peripheral arterial occlusive disease (PAD).
  • To highlight the impact of drug-eluting balloons in reducing restenosis rates, especially in femoropopliteal lesions.
  • To explore potential combination therapies, such as plaque removal followed by drug-eluting balloons, for PAD treatment.

Summary:

  • Intervention-based revascularization is the preferred strategy for most PAD cases, ideally managed in a multidisciplinary vascular center.
  • Drug-eluting balloons have demonstrated substantial success in mitigating restenosis, a key challenge in endovascular PAD therapy.
  • Combination therapies involving plaque removal and drug-eluting balloons present a potential advancement, though economic considerations are crucial.

Impact:

  • Improved patient outcomes through reduced restenosis rates and enhanced long-term efficacy of endovascular PAD treatments.
  • Potential for optimized treatment algorithms by integrating novel technologies like drug-eluting balloons and plaque removal techniques.
  • Informs clinical decision-making and future research directions in the management of peripheral arterial occlusive disease.