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Wave Intensity Analysis Can Identify Eccentric Cardiac Hypertrophy in Hypertensive Patients With Varied Left

Guo-Qing Du1, Hai-Ru Li1, Jing-Yi Xue1

  • 1Department of Ultrasound, Second Affiliated Hospital of Harbin Medical University, Harbin, China (G.-Q.D., H.-R.L., S.C., P.D., Y.W., J.-W.T.); and Department of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China (J.-Y.X.).

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
|October 4, 2015
PubMed

Insights

Wave intensity analysis, specifically the R-W1/W1-W2 ratio, can effectively identify eccentric hypertrophy in hypertensive patients. This noninvasive method offers an alternative to echocardiography for diagnosing this condition.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Hypertension Research

Background:

  • Essential hypertension is associated with various left ventricular (LV) configurations.
  • Eccentric hypertrophy is a significant LV remodeling pattern in hypertensive patients.
  • Distinguishing between different LV configurations is crucial for patient management.

Purpose of the Study:

  • To evaluate the efficacy of wave intensity analysis in discriminating eccentric hypertrophy among hypertensive patients.
  • To assess if wave intensity parameters can differentiate varied left ventricular configurations.

Main Methods:

  • A cohort of 155 hypertensive patients with diverse LV configurations was studied.
  • Noninvasive wave intensity analysis of the common carotid artery was performed.
  • Echocardiography, blood pressure, and flow velocity measurements were utilized.

Main Results:

  • Patients with eccentric hypertrophy exhibited significantly lower left ventricular ejection fraction (LVEF).
  • The R-W1/W1-W2 ratio was markedly higher in the eccentric hypertrophy group compared to others.
  • No significant differences were observed in W1, W2, or negative area across groups.

Conclusions:

  • The R-W1/W1-W2 ratio derived from wave intensity analysis can identify eccentric hypertrophy in hypertensive patients.
  • This noninvasive approach may obviate the need for echocardiography in diagnosing this condition.
Abstract

Keywords:
blood pressureechocardiographyhypertensionleft ventricular configurationwave intensity

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