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Updated: Apr 1, 2026
A Method for High Fidelity Optogenetic Control of Individual Pyramidal Neurons In vivo
Published on: September 2, 2013
Spotlighted Brains: Optogenetic Activation and Silencing of Neurons
Arash Kianianmomeni1, Armin Hallmann1
1Department of Cellular and Developmental Biology of Plants, University of Bielefeld, Universitätsstrasse 25, D-33615 Bielefeld, Germany.
Abstract:
Optogenetics is revolutionizing cell biology and neuroscience research by allowing precise biochemical control of neuronal activity through light-activated channels. Light-induced ion transporters have been used extensively for cellular activation, and now light-gated inhibitory channels have been discovered. These represent a key new tool to elucidate the molecular mechanisms underlying neurological and neuropsychiatric disorders.
