Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A computerized program of skin test evaluation and its predictive value in immunotherapy.

G Bagnato1, M Bottari, G Siragusa

  • 1Department of Internal Medicine, University of Messina, Italy.

Annals of Allergy
|January 1, 1989
PubMed
Summary

A new computerized skin testing method accurately predicts adverse reactions during hyposensitization therapy. This sensitive and reproducible technique identified at-risk patients, improving safety for allergy immunotherapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of eggshell density of fertile eggs and infectious bronchitis virus on performance and sanitary parameters of embryos and broilers.

British poultry science·2026
Same author

Sexual abuse or traffic accidental trauma? Analysis of a case.

La Clinica terapeutica·2025
Same author

Cardiac valve hemangioma in two cases of sudden infant death.

La Clinica terapeutica·2025
Same author

Relationship between interleukin 1 (IL-1) genetic polymorphism and periimplantitis: systematic literature review and meta-analysis.

European review for medical and pharmacological sciences·2024
Same author

Effect of glycoelectrolytic supplement on post-weaning piglet performance and intestinal integrity.

Tropical animal health and production·2023
Same author

Long-acting injectable progesterone treatment prior to puberty induction in gilts.

Domestic animal endocrinology·2023

Area of Science:

  • Allergy and Immunology
  • Dermatology
  • Computational Biology

Background:

  • Hyposensitization therapy carries risks of adverse reactions.
  • Predicting patient susceptibility to these reactions is crucial for safety.
  • Current methods for assessing skin test responses may lack sensitivity or reproducibility.

Purpose of the Study:

  • To introduce a novel computerized methodology for specific skin testing.
  • To assess the sensitivity and reproducibility of this new technique.
  • To evaluate its predictive value in identifying patients at high risk for adverse reactions during hyposensitization.

Main Methods:

  • Development of a computerized system for skin test assessment.
  • Evaluation of the system's sensitivity and reproducibility.

Related Experiment Videos

  • Application of the technique to identify patients with unusual dermal responses.

    • Main Results:

    • The computerized skin testing methodology proved to be sensitive and reproducible.
    • An unusual dermal response was detected in 11 out of 93 patients.
    • These 11 patients subsequently experienced generalized or local generalized adverse reactions.

    Conclusions:

    • The computerized skin testing approach is effective in predicting adverse reactions.
    • This method enhances patient safety during hyposensitization.
    • It offers a valuable tool for risk stratification in allergy immunotherapy.