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Diagnosis and Management of Cutaneous B-cell Lymphoma
1Department of Internal Medicine, Division of Hematology-Oncology, Geffen School of Medicine, University of California, Los Angeles, 2020 Santa Monica Suite 600, Santa Monica, CA 90404, USA.
Abstract:
The diagnosis of primary cutaneous B-cell lymphoma (CBCL) requires that the search for a more widespread lymphoma has been negative. The clinical presentation, outlook, and treatment options of the common types of CBCLs, with emphasis on differences or similarities to their nodal counterparts, are discussed. Treatment may range from observation to topical therapies to systemic therapies, depending on the histology, degree and area of skin involvement, patient performance, and comorbidities. Rare lymphomas, such as intravascular large B-cell lymphoma and Epstein-Barr virus-positive cutaneous lymphoproliferations that are associated with immunodeficiency, are also briefly described.
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