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Published on: July 5, 2021
Pediatric aggressive giant cell granuloma of nasal cavity
Sung Tae Seo1, Ki Ryun Kwon1, Ki-Sang Rha1
1Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, South Korea; Research Institute for Medical Science, Chungnam National University School of Medicine, Daejeon, South Korea.
Introduction:
Giant cell granuloma (GCG) is a non-neoplastic osseous proliferative lesion of unknown etiology. Although a benign disease process, GCG can be locally destructive. It is extremely rare to have a pediatric case of GCG occurring in the nasal cavity with intracranial invasion.
Presentation Of Case:
We report a case of an aggressive and recurrent giant cell granuloma with intracranial invasion in a 10 years old female patient which was completely excised with endoscopic craniofacial resection.
Discussion:
A literature review on pathogenesis, diagnosis and management is also performed.
Conclusion:
The most common treatment for giant cell granuloma is surgery, ranging from simple curettage to resection. However, it must be completely excised in cases of aggressive and extensive lesion because of the high recurrence rate after incomplete removal.
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