Related Experiment Video
Updated: Apr 1, 2026
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Use of a Soft Silicone Foam Dressing to Change the Trajectory of Destruction Associated with Suspected Deep Tissue
Purpose:
To explore the evolution of suspected deep tissue injury (sDTI) pressure ulcers and identify the role of early identification and intervention in hindering tissue destruction. In contrast to previously published evidence, the foundational research identified a significant trend of sDTI recovery which warranted further analysis.
Subjects And Settings:
A single-site, 24-month retrospective, IRB-approved study evaluated 77 adult (age 18 or older) hospitalized subjects with 128 wound care nurse-identified sDTIs over the course of 1 day to 14 weeks for 377 encounters.
Methods:
Data from a 24-month period (2010-2012) were analyzed during the primary study. In addition to demographics, the evolution process including site, initial presentation, measurements, tissue consistency, and treatment, were assessed. In response to findings of significant sDTI recovery, a secondary in-depth analysis focused on commonalities and variables for clarity of their contribution to the isolated improved patient outcomes.
Results:
In addition to clearer delineation of demographics, co-morbid conditions, and evolutionary patterns, the researcher identified patient outcomes in stark contrast to those previously published in the literature. A significant outcome of resolution of sDTI pressure ulcers was observed. Upon further review, the role of absorbent soft silicone, multi-layer, self-adherent bordered foam (Mepilex) in these outcomes was elucidated clearly.
