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Updated: Apr 1, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Case Report: Prothesis-patient mismatch after aortic valve replacement
Patient-prosthesis mismatch (PPM) after heart valve replacement can lead to heart failure. Early identification of patients at risk for PPM is crucial to improve clinical outcomes and reduce healthcare costs.
Area of Science:
- Cardiology
- Biomedical Engineering
- Cardiac Surgery
Background:
- Prosthetic heart valves (PHVs) are smaller than native valves, leading to inherent stenosis.
- Accurate PHV sizing and selection are critical to avoid complications and ensure optimal hemodynamics.
- Patient-prosthesis mismatch (PPM) is a recognized long-term complication with significant clinical consequences.
Observation:
- A 78-year-old male patient underwent aortic valve replacement for severe aortic stenosis.
- The patient experienced recurrent shortness of breath and decompensated congestive heart failure (CHF) post-surgery.
- These complications suggest a potential issue with patient-prosthesis mismatch.
Findings:
- PPM evaluation is insufficiently emphasized in clinical practice.
- Failure to recognize PPM can result in hemodynamic impairment and clinical deterioration.
- This case highlights the importance of pre-operative assessment for PPM risk.
Implications:
- Identifying patients at risk for PPM can decrease its prevalence and associated healthcare costs.
- Standardized pre-operative protocols are needed to minimize the risk of PPM.
- Addressing PPM proactively can improve long-term clinical outcomes and reduce morbidity and mortality.
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