Related Experiment Video
Updated: Apr 1, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
Published on: July 8, 2021
Calcium silicate-based cements: composition, properties, and clinical applications
Alaa E Dawood1, Peter Parashos1, Rebecca H K Wong1
1Melbourne Dental School, Oral Health Cooperative Research Centre, University of Melbourne, Melbourne, Vic., Australia.
Abstract:
Mineral trioxide aggregate (MTA) is a calcium silicate-based cement (CSC) commonly used in endodontic procedures involving pulpal regeneration and hard tissue repair, such as pulp capping, pulpotomy, apexogenesis, apexification, perforation repair, and root-end filling. Despite the superior laboratory and clinical performance of MTA in comparison with previous endodontic repair cements, such as Ca(OH)2 , MTA has poor handling properties and a long setting time. New CSC have been commercially launched and marketed to overcome the limitations of MTA. The aim of the present review was to explore the available literature on new CSC products, and to give evidence-based recommendations for the clinical use of these materials. Within the limitations of the available data in the literature regarding the properties and performance of the new CSC, the newer products could be promising alternatives to MTA; however, further research is required to support this assumption.
Related Concept Videos
Hydration of Cement
Types of Cement I
Type I (Ordinary Portland Cement) is widely used for general construction where special properties are not required. It has moderate sulfate resistance and heat of hydration.
Type II (Modified Cement) offers moderate resistance to sulfate attack and a lower rate of heat development compared to Type I. It is suitable for structures in...
Types of Cement II
Soundness of Cement
Aggregate Cement Ratio
Pozzolans
Fly ash is...

