Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

3.0K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
3.0K
Cancer Therapies02:49

Cancer Therapies

10.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.6K
Cancer Therapies02:49

Cancer Therapies

3.0K
3.0K
Cancer Survival Analysis01:21

Cancer Survival Analysis

832
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
832
Cancer02:18

Cancer

55.8K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
55.8K
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

935
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
935

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can the Health Care System Manage Increased Workloads From Expanded Access to Cancer Treatment?

JAMA network open·2021
Same author

Metal(loid) speciation and transformation by aerobic methanotrophs.

Microbiome·2021
Same author

Total Pain #417.

Journal of palliative medicine·2021
Same author

Incorporating palliative care into oncology practice: why and how.

Clinical advances in hematology & oncology : H&O·2021
Same author

How palliative care teams can mitigate financial toxicity in cancer care.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2021
Same author

In Reply to Nieder.

International journal of radiation oncology, biology, physics·2021

Related Experiment Video

Updated: Apr 1, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

10.0K

Cancer Pain Management.

Thomas J Smith1, Catherine B Saiki1

  • 1Harry J. Duffey Family Palliative Care Program of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medical Institutions, Baltimore, MD.

Mayo Clinic Proceedings
|October 6, 2015
PubMed
Summary
This summary is machine-generated.

Effective cancer pain management remains a challenge, impacting patient quality of life. This overview covers pain mechanisms and current/emerging treatments for better cancer pain control.

More Related Videos

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

2.5K

Related Experiment Videos

Last Updated: Apr 1, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

10.0K
Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
05:56

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

Published on: June 21, 2024

2.5K

Area of Science:

  • Oncology
  • Pain Medicine
  • Palliative Care

Background:

  • Cancer-related pain affects nearly half of patients, significantly impacting quality of life.
  • Despite advancements, pain management in cancer care has seen little improvement over the past two decades.
  • Suboptimal pain management stems from limited provider training, overestimation of skills, and inadequate referrals to pain specialists.

Purpose of the Study:

  • To provide a comprehensive overview of cancer-related pain mechanisms and types.
  • To review current, novel, and promising strategies for managing cancer pain.
  • To emphasize the importance of effective pain assessment and evidence-based treatment.

Main Methods:

  • Review of existing literature on cancer pain mechanisms.
  • Analysis of current pharmacological and non-pharmacological pain management modalities.
  • Exploration of emerging and interventional pain treatment approaches.

Main Results:

  • Cancer pain management remains a significant unmet need in oncology care.
  • A multimodal approach, including pharmacological agents and non-drug interventions, is crucial.
  • Early and accurate pain assessment is fundamental for effective treatment.

Conclusions:

  • Improving cancer pain management requires enhanced provider education and timely specialist referrals.
  • A thorough understanding of pain mechanisms guides the selection of appropriate interventions.
  • Optimizing cancer pain control is essential for enhancing patient quality of life and overall care.