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Updated: Apr 1, 2026

Processing of Human Reduction Mammoplasty and Mastectomy Tissues for Cell Culture
Published on: January 3, 2013
Reduction Mammoplasty: A Comparison Between Operations Performed by Plastic Surgery and General Surgery
Anthony M Kordahi1, Ian C Hoppe2, Edward S Lee2
1Rutgers-New Jersey Medical School, Newark.
Plastic surgeons performed more reduction mammoplasties than general surgeons, with similar complication rates. However, general surgery patients had higher rates of skin flap failure and longer operative times, suggesting specialized training is beneficial.
Area of Science:
- Plastic Surgery
- General Surgery
- Surgical Outcomes
Background:
- Reduction mammoplasty is a common procedure performed by both plastic and general surgeons.
- Debate exists regarding whether this procedure should remain exclusive to surgical specialists.
- The National Surgical Quality Improvement Project (NSQIP) offers data to compare outcomes between specialties.
Purpose of the Study:
- To compare preoperative comorbidities and 30-day postoperative complications of reduction mammoplasty performed by general surgery versus plastic surgery.
- To evaluate the impact of surgical specialty on patient outcomes in reduction mammoplasty.
Main Methods:
- Utilized the NSQIP database from 2005-2012, identifying reduction mammoplasties (CPT codes) in female patients with breast hypertrophy (ICD-9 code 611.1).
- Collected data on patient demographics, preoperative variables, and specific postoperative outcomes including infections, dehiscence, pulmonary complications, and reoperation.
- Compared outcomes between procedures performed by general surgery and plastic surgery specialists.
Main Results:
- A total of 6,239 reduction mammoplasties were analyzed: 339 by general surgery and 5,900 by plastic surgery.
- No significant differences were found in superficial or deep surgical site infections, organ space infections, or wound dehiscence between the groups.
- General surgery patients experienced a higher likelihood of skin flap failure requiring reoperation (P < .05) and had longer operative times (P < .05).
Conclusions:
- While overall complication rates were similar, specific adverse events like skin flap failure were more frequent in reduction mammoplasties performed by general surgeons.
- These findings suggest that focused training in reduction mammoplasty, as typically received by plastic surgeons, may offer patient benefits.
- Limitations include the absence of long-term data on aesthetic outcomes, nipple sensation, and late wound complications.
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