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Amphotericin B Resistant Apophysomyces elegans Causing Rhino-oculo-Cerebral Mucormycosis in an Immunocompetent Host

Debasis Biswas1, Aarti Kotwal2, Barnali Kakati2

  • 1Professor, Department of Microbiology, Himalayan Institute of Medical Sciences , Jolly Grant, Dehradun, India; Additional Professor, Department of Microbiology, AIIMS Bhopal, Bhopal, India .

Journal of Clinical and Diagnostic Research : JCDR
|October 6, 2015
PubMed

Insights

Rhino-oculo-cerebral mucormycosis (ROCM) is an emerging fungal infection. This case highlights Apophysomyces elegans resistance to Amphotericin B, complicating treatment for diabetic patients.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Mucormycosis is a serious angioinvasive fungal infection caused by Mucorales.
  • Rhino-oculo-cerebral mucormycosis (ROCM) is a common presentation, particularly in uncontrolled diabetes.
  • Rising incidence of mucormycosis necessitates understanding treatment challenges.
Keywords:
Antifungal susceptibility profileDiabetesMucormycosis

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