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A Survivor of Neonatal Intestinal Mucormycosis

Pragati Aditya Sathe1, Ratnaprabha Kundlikrao Ghodke2, Bhuvaneshwari Mahendra Kandalkar3

  • 1Associate Professor, Department of Pathology, Seth G. S. Medical College and KEM Hospital , Mumbai, India .

Journal of Clinical and Diagnostic Research : JCDR
|October 6, 2015
PubMed

Insights

Gastrointestinal mucormycosis (GIM) is a rare fungal infection in infants, often mistaken for necrotizing enterocolitis (NEC). This case highlights a rare infant survivor, emphasizing early diagnosis for effective treatment.

Area of Science:

  • Medical Mycology
  • Pediatric Infectious Diseases
  • Gastroenterology

Background:

  • Gastrointestinal mucormycosis (GIM) is a rare, life-threatening opportunistic fungal infection.
  • Infants represent a significant portion of pediatric GIM cases, often presenting with symptoms mimicking necrotizing enterocolitis (NEC).
  • Accurate differentiation between GIM and NEC is critical due to vastly different treatment protocols.

Observation:

  • A neonate presented with clinical signs suggestive of gastrointestinal distress.
  • Diagnostic challenges included distinguishing GIM from more common conditions like NEC.
  • The neonate received specific antifungal treatment.

Findings:

  • The case details a rare instance of a neonate diagnosed with GIM.
  • The neonate survived the infection, which typically carries a high mortality rate.
  • Successful management required prompt clinical suspicion and pathological confirmation.

Implications:

  • This case underscores the importance of a high index of suspicion for GIM in neonates presenting with gastrointestinal symptoms.
  • Early diagnosis and appropriate antifungal therapy are crucial for improving outcomes in GIM.
  • Further research into GIM in neonates may improve diagnostic strategies and treatment efficacy.
Keywords:
EnterocolitisFungalLaparotomy

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