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Updated: Apr 1, 2026

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Heart and Lung Metastases From Endometrial Stromal Sarcoma in a Forty-Two-Year-Old Woman
Behnam Shakerian1, Mohammad Hossein Mandegar1, Bahieh Moradi2
1Department of Cardiothoracic Surgery, Shariati General Hospital, Tehran University of Medical Sciences, Tehran, IR Iran.
Introduction:
Low-grade endometrial stromal sarcoma (LG-ESS) is a malignant intrauterine tumor that rarely presents with distant metastasis. Simultaneous lung and cardiac metastases from LG-ESS is also an extremely rare event.
Case Presentation:
A 42-year-old woman presented with dyspnea and exercise intolerance. She had a history of hysterectomy and left salpingoophorectomy. She underwent second laparotomy as well as right oophorectomy after new finding of vaginal mass with histopathologic diagnosis of LG-ESS. Cardiac imaging techniques demonstrated tumoral process in the right atrium and ventricle, coronary sinus, and pulmonary outlet tract as well as multiple metastases in the lung fields. Successful complete surgical resection of the metastatic tumor in the right side of the heart and then radiotherapy were done. After 28 months, follow-up examination revealed no abnormality.
Conclusions:
We describe the first documented case of isolated intracardiac and lung metastases of a LG-ESS without concurrent abdominal or caval metastasis.
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