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Updated: Apr 1, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
Nasopalpebral Schwannomas and Human Immunodeficiency Virus Infection
Adriana Handra-Luca1, Djamel Haddar, Anne-Sophie Morin
1Service d'Anatomie Pathologique, Assistance Publique - Hopitaux de Paris (AP-HP), Universitx00E9; Paris Nord Sorbonne Citx00E9;, Bobigny, France.
Objective:
To report a case of a schwannoma of nasopalpebral location, occurring in a human immunodeficiency virus (HIV)-positive patient.
Clinical Presentation And Intervention:
A 55-year-old man presented with a nasopalpebral painless tumefaction, pneumopathy and HIV-related immunodepression after stopping combination antiretroviral therapy. Magnetic resonance imaging showed subcutaneous masses, with contrast enhancement of the left nose pyramid, internal cantus and inferior palpebral area, suspicious of Kaposi sarcoma. The resected specimen showed schwannoma histology, with tumor cells expressing S100 protein and WT1.
Conclusion:
The features of a rare case of facial schwannoma of nasopalpebral location in an HIV-positive patient are reported. The diagnosis may be difficult before microscopic examination, with imaging features suggesting a Kaposi sarcoma.
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